{"product_id":"perglim-m2-glimepiride-metformin","title":"Perglim-M2 (Glimepiride + Metformin)","description":"\u003cp\u003eGlimepiride + Metformin is an oral antidiabetic combination therapy used to manage type 2 diabetes mellitus when diet, exercise, or single-drug therapy alone are insufficient.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGlimepiride (a sulfonylurea) works by stimulating the pancreas to release more insulin.\u003c\/li\u003e\n\u003cli\u003eMetformin (a biguanide) reduces hepatic glucose production and improves peripheral insulin sensitivity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTogether, they provide a synergistic effect, improving blood sugar control and reducing the risk of long-term diabetes-related complications.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMain Uses\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eManagement of type 2 diabetes mellitus\u003c\/li\u003e\n\u003cli\u003eHelps lower fasting and postprandial blood glucose levels\u003c\/li\u003e\n\u003cli\u003eReduces risk of microvascular and macrovascular complications of diabetes\u003c\/li\u003e\n\u003cli\u003eBeneficial for patients not controlled on metformin or glimepiride alone\u003c\/li\u003e\n\u003cli\u003eImproves glycemic control in overweight or obese patients\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eContraindications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis combination should be avoided in patients with:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eType 1 diabetes mellitus\u003c\/li\u003e\n\u003cli\u003eDiabetic ketoacidosis (DKA) with or without coma\u003c\/li\u003e\n\u003cli\u003eSevere renal impairment (eGFR \u0026lt;30 mL\/min\/1.73 m²)\u003c\/li\u003e\n\u003cli\u003eSevere hepatic impairment\u003c\/li\u003e\n\u003cli\u003eHypersensitivity to glimepiride, metformin, sulfonylureas, or sulfonamides\u003c\/li\u003e\n\u003cli\u003eConditions predisposing to hypoxia (cardiac\/respiratory failure, recent myocardial infarction, shock)\u003c\/li\u003e\n\u003cli\u003eAlcohol abuse (increases risk of lactic acidosis with metformin)\u003c\/li\u003e\n\u003cli\u003ePregnancy and lactation (unless specifically recommended by a physician)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDosage: \u003c\/strong\u003eThe dosage of this medicine depends on the prescription and instruction given by the doctor.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrecautions:\u003c\/strong\u003e Do not take this medicine without any medical consultation with your doctor.\u003c\/p\u003e","brand":"Mega Philippines","offers":[{"title":"Tablet (2 mg + 500 mg) in Box of 100's","offer_id":48942541406345,"sku":"202507271538","price":2470.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0789\/6550\/6185\/files\/PERGLIM-COMPOSE-1-1.jpg?v=1794275392","url":"https:\/\/shoplumvella.shop\/products\/perglim-m2-glimepiride-metformin","provider":"Elmwood Trading","version":"1.0","type":"link"}