{"product_id":"hentaxel-docetaxel","title":"Hentaxel (Docetaxel)","description":"\u003ch1\u003eDocetaxel: Potent Chemotherapy Targeting Cell Division\u003cbr\u003e\n\u003c\/h1\u003e\n\u003cp\u003eDocetaxel is a clinically established chemotherapy drug used to treat several cancers, including breast, ovarian, prostate, stomach, non-small-cell lung cancer (NSCLC), and cancers of the head and neck. It belongs to the taxane class of antimitotic agents and is a semisynthetic analogue of paclitaxel.\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eHow It Works:\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003eDocetaxel binds to microtubules in a 1:1 ratio, stabilizing their structure and preventing depolymerization. This action disrupts cell division and promotes cancer cell death. Compared to paclitaxel, docetaxel is twice as effective in inhibiting microtubule breakdown, though it does not bind to dimeric tubulin.\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eAdministration:\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003eThe drug is delivered via slow intravenous infusion and may be used as monotherapy or in combination with other anticancer agents.\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003ePotential Side Effects:\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003eCommon: Hair loss, low blood cell counts (cytopenia), muscle pain, nausea, vomiting, fatigue, and sensory issues like numbness or shortness of breath.\u003cbr\u003e- Severe: Liver toxicity, hypersensitivity reactions, fluid retention, neutropenic colitis, embryo-fetal harm, pneumotoxicity, and risk of developing secondary cancers.\u003cbr\u003e- Docetaxel’s adverse effects tend to be more pronounced in patients with liver impairment.\u003c\/p\u003e\n\u003ch2\u003eImportant Notes:\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003eUse in pregnancy is contraindicated due to fetal risks, and careful monitoring is recommended to detect serious complications like pneumotoxicity early.\u003c\/p\u003e","brand":"Goodfellow","offers":[{"title":"(40mg\/mL) Solution for Injection in 0.5mL Glass Vial 1's","offer_id":48942560673929,"sku":"20240614000","price":7300.0,"currency_code":"USD","in_stock":true},{"title":"(40mg\/mL) Solution for Injection in 2mL Glass Vial 1's","offer_id":48942560706697,"sku":"20240614001","price":29000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0789\/6550\/6185\/files\/docetaxel.png?v=1794275528","url":"https:\/\/shoplumvella.shop\/products\/hentaxel-docetaxel","provider":"Elmwood Trading","version":"1.0","type":"link"}